Models and mechanisms of Bornavirus pathogenesis
نویسندگان
چکیده
Borna Disease Virus (BDV) causes neurologic disease in a wide variety of warm-blooded animals. Although human infection has not been conclusively demonstrated, some surveys suggest that BDV or a related agent might infect humans and be implicated in mental illness. Recent progress in tissue culture and animal models reveals insights into the molecular biology of this unique virus and unveils mechanisms by which persistent, non-cytolytic viral infection can cause behavioral disorders.
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تاریخ انتشار 2004